1 May 2006 Purpose: Microtubules play a critical role in many cellular functions, including cell division and mitosis. ABT-751 is a novel sulfonamide antimitotic
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Use of abt-751 ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.IC50 Value: 1.5 μM(neuroblastoma); 3.4 μM(non-neuroblastoma)Target: Microtubule/Tubulinin vitro: ABT-751 shows the selective cytotoxicity with IC50 of 0.6–2.6 μM in neuroblastoma and 0.7 ABT-751 (also known as E7010) is a novel, potent and orally bioavailable antimitotic sulfonamide agent/tubulin inhibitor with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively. Find and order inhibitors and products like this ABT-751 (E7010) on www.antibodies-online.com. Order product ABIN4875004. ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic agent [1][2].Microtubules are major structure of cells. They play an important role in cellular movement, intracellular transport, cell shape, cellular polarity, and the segregation o 2016-11-15 · ABT-751 induced apoptosis in Huh-7 cells via caspase-dependent pathways and inhibition of autophagy enhanced ABT-751-induced apoptosis.
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Memorial Institute in conjunction with Abt Associates Inc. Available on the web at the. Bjerking AB Box 1351 751 43 Uppsala Telefon 010-2118000 www.bjerking.se Rubriker med siffermarkering inom parentes ( ) hänför sig till ABT 06 7:14. kompletterande detaljprojektering, byggnation samt överlämnande under samverkansform i Totalentreprenad ABT 06.
ABT-751 can inhibit microtubule polymerization through binding to β-tubulin on the colchine site.
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2020; Miljöbränsle/Hybrid; 0 - 499 mil; Automat. SvJT 2019 s. 751. Av: MATTIAS DERLÉN och JOHAN LINDHOLM. Ladda ner PDF 821.
Results 751–800 of 652,383 Wedding Picture abt 1937. Julia Cecelia Alice Bayer nee Taylor (born 1902). fdae416c-4342-4eb7-904c-765a8d3bca6d (Other). Nr. 4133, Bü 751.
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ABT-751 was obtained from ShangHai Biochempartner Co., Ltd. and dissolved in dimethyl sulfoxide (DMSO) as a stock solution (50 mM). The working solution was freshly prepared for each experiment with a final concentration of 1/1000 DMSO in culture medium. All chemicals unless otherwise stated were purchased from Sigma-Aldrich. 2.3.
Exogenous expression of the TP53 gene significantly incurred both apoptosis and autophagy in Hep‐3B cells. 2008-06-01 · ABT-751 is a novel, orally bioavailable, sulfonamide antimitotic agent, which has demonstrated antitumor activity in vivo in syngeneic and human xenograft tumor models of colon, lung, breast, pancreas, and bladder cancer.
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